Study about the event-related potential P300 and cognitive function in patients with Methamphetamine dependence
Bibliographic record
Abstract
Objective To investigate the impairment of cognitive function and the feature of event related potential P300(ERP P300) in patients with Methamphetamine dependence.Methods 30 patients aged 18 to 65 years old with Methamphetamine dependence(study group) and 30 well-matched healthy individuals(control group) were assessed with Montreal cognitive assessment(MoCA) and ERP P300.The performance of MoCA and the parameters of ERP P300 were compared between the two groups.Results The latencies of P2,N2,P3 in CZ,as well as the latencies of N1,N2,P2,P3 in PZ were significantly longer in study group than those in control group(P0.05 or P0.01).The amplitudes of CZ and PZ were significantly lower in study group than those in control group(P0.05 or P0.01).Total score and 7 factor scores of MoCA in study group were significantly lower than those in control group(P0.05 or P0.01).In study group,the latencies of N1,N2,P2,P3 in PZ were significantly negatively correlated with total score and factor scores of MoCA(P0.05 or P0.01),the amplitude of PZ were significantly positively correlated with total score and factor scores of MoCA(P0.05 or P0.01).Conclusion The cognitive function is impaired in patients with methamphetamine dependence.Event-related potential P300 can be used as an objective index to assess the impairment of cognitive function in patients with Methamphetamine dependence.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".