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Record W2352271501

Expression of AQP 1,2 Proteins in Kidney of Filial Meriones meridianus

2014· article· en· W2352271501 on OpenAlexaff
Chun Zhang

Bibliographic record

VenueDongwuxue zazhi · 2014
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPlant Toxicity and Pharmacological Properties
Canadian institutionsScience North
Fundersnot available
KeywordsKidneyBiologyAquaporin 2ReabsorptionImmunohistochemistryInternal medicineDistal convoluted tubuleEndocrinologyDuct (anatomy)Aquaporin 1Medullary cavityAnatomyMedicineImmunologyWater channel
DOInot available

Abstract

fetched live from OpenAlex

The expression of AQP1, 2 in kidney of filial Meriones meridianus was investigated by immunohistochemistry combined with stereological method,and the expression intensity of AQP1,2 was analyzed by IPP professional image analysis software. Results showed that there was expression of AQP1,2 in kidney of filial M. meridianus at postnatal day 1,7,14,21,and 32. AQP1 immunopositive cells mainly distributed in the epithelial cells of proximal convoluted tubule and thin segment of medullary loop in kidney at postnatal day 1,7,14,21,and 32,while AQP2 expressed on the apical plasma membrane of collecting duct principal cells at postnatal day 1,7,14,21,and 32. Surface area density and average optical density of AQP1 positive cells in proximal convoluted tubule and thin segment of medullary loop and AQP2 positive cells in collecting duct in kidney of filial M. meridianus increased( P 0. 05 or P 0. 01) at postnatal 7 day,but there was no significant difference from postnatal day 7 to postnatal day 32( P 0. 05). The results showed that the expression level of AQP1,2 positive cells in kidney of filial M. meridianus increased at postnatal day 7,when the ability of water reabsorption of proximal convoluted tubule,thin segment of medullary loop and collecting duct increased. AQP1,2 might play an important role in urine concentrating of filial M. meridianus kidney to regulate the balance of water in kidney.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.290

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.241
Teacher spread0.227 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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