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Record W2352351248

Genetic Polymorphism of Nogo Gene in Han Chinese of Chengdu and Thai Populations

2011· article· en· W2352351248 on OpenAlex
YU Yingxi

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueLife Science Research · 2011
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
Topic14-3-3 protein interactions
Canadian institutionsnot available
Fundersnot available
KeywordsGenotypeAlleleBiologyGeneticsAllele frequencyGenotype frequencyGenePolymorphism (computer science)
DOInot available

Abstract

fetched live from OpenAlex

Neurite growth inhibitor(Nogo) play a major role in inhibiting axonal regeneration in the central nervous system.TATA and CAA insertion deletion polymorphism is related to risk of chronic schizophrenia.RTN4 genotype and allele frequency distribution is differences in various ethnic.The genotypes and allele frequencies of Nogo gene TATC deletion and CAA insertion were analyzed in 205 healthy Han Chinese of Chengdu and 101 Thai individuals using polymerase chain reaction-polyacrylamide gel electrophoresis strat-egy and DNA sequencing.The frequency of the(TATC)2(TATC)2 genotype of TATA deletion was 10.2% in Han Chinese of Chengdu,which was significantly lower than that in Thai population.The frequency of the(TATC)2 allele was 34.9% in Han Chinese of Chengdu,which was significantly lower than that in Thai popu-lation as well.However,there was no significant difference in the genotype and allele frequency of CAA in-sertion between Han Chinese of Chengdu and Thai population.Additionally,the frequency of(TATC)2 allele was significantly lower than that in French-Canadian and Tunisian,which was 45.0% and 49.0% respective-ly.The frequency of(CAA)2 allele was 66.8%,which was significantly higher than that in French-Canadian and Brazilian(53.0% and 37.8%,respectively).The results suggested that TATC deletion and CAA insertion of Nogo gene in diverse populations is significantly different.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.422
Threshold uncertainty score0.319

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.112
GPT teacher head0.404
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it