MétaCan
Menu
Back to cohort
Record W2353123667

Comparison between clonidine and midazolam as premedication in children

2005· article· en· W2353123667 on OpenAlexaboutno aff
Ma Chang

Bibliographic record

VenueZhongguo fuyou baojian · 2005
Typearticle
Languageen
FieldMedicine
TopicAnesthesia and Sedative Agents
Canadian institutionsnot available
Fundersnot available
KeywordsMedicinePremedicationShiveringSedationAnesthesiaClonidineMidazolamIncidence (geometry)Emergence deliriumVomitingPain scaleRandomized controlled trialSurgery
DOInot available

Abstract

fetched live from OpenAlex

Objective:To compare effect of clonidine a nd midazolam as premedication using a prospective, randomized and double-blind des ign. Methods:100 children patients scheduled for circumcision w ith ASA physical status 1 grade (aged 1~11 years) were divided at random M group (n=52) received midazolam 300 μg/kg and atropine 40μg/kg and C group (n =48) received clonidine 5 μg/kg and atropine 40 μg/kg, both groups given rec tal application. The incidence of immediate postoperative pain (0~2 h) was asse ssed by repeated Objective Pain Scale (OPS) scores. Degree of sedation (modifie d Vancouver sedation scale 0~3), occurrence of postoperative vomiting (POV), and incidence of shivering and immediate postoperative confusion was registered as end-points. Parents were instructed to continue the evaluation of pain, sedatio n, POV and sleep during a 24-h period. Parents were also asked for their prefer ence concerning the postoperative behavior of their child (calm, sedated, VS ale rt, active). Results:OPS scores (median=8.0) in C group significantly decreased than that of M group M (median=11.5) (P=0.011). Early postopera tive sedation score (median=13) in C group slightly increased than that of M gro up (median=12)(P0.01). No episode of shivering was observed in the C grou p but was present in five of the patients in M group (P=0.057). In younger children (5 years), the incidence of postoperative confusion was lower in C gr oup than that in M group (P=0.001). No difference in the frequencies of PO V incidences, need for analgesic and sleep mode of postoperative hours could be observed between two groups according to parents' evaluation in the first 24 hou rs, the calm and sedated degree in C group were better than those in M group ( P=0.024). Conclusion:Rectal premedication with clonidine could signi ficantly reduce postoperative early pain comparing to midazolam with moderately increased sedation during the first 24 postoperative hours.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.327
Teacher spread0.306 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2005
Admission routes1
Has abstractyes

Explore more

Same venueZhongguo fuyou baojianSame topicAnesthesia and Sedative AgentsFrench-language works237,207