MétaCan
Menu
Back to cohort
Record W2354272507

Establishment and optimization of RAMP-PCR reaction system for DNA of Eupolyphaga sinensis

2014· article· en· W2354272507 on OpenAlex
Wang Hu

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueZhongcaoyao · 2014
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMolecular Biology Techniques and Applications
Canadian institutionsScience North
Fundersnot available
KeywordsPrimer (cosmetics)RAPDgenomic DNAPolymerase chain reactionBiologyMolecular biologyDNADNA extractionMicrosatelliteGenetic diversityTaq polymeraseGeneticsPolymeraseChemistryGeneThermus aquaticusMedicinePopulationAllele
DOInot available

Abstract

fetched live from OpenAlex

Objective To provide the basis for the genetic diversity research of Eupolyphaga sinensis by establishing and optimizing the random amplified microsatellite polymorphism RAMP-PCR reaction system and amplification procedure for genomic DNA.Methods Phenol chloroform extraction of genomic DNA was performed on female E.sinensis.Based on RAMP Primer(ISSR807 + RAPD A5),the orthogonal test was adopted to optimize the RAMP-PCR amplification system on E.sinensis in five factors(Mg2+,dNTPs,primer,Taq DNA polymerase,and template DNA) at four levels,and the suitable anneal temperature of the primer was selected.Results The optimal Primer(ISSR807+RAPD A5) for RAMP-PCR system(25 μL reaction volume) of E.sinensis was:10 × PCR buffer(2.5 μL),Mg2+(1.0 mmol/L),dNTPs(2.0 mmol/L),primer(0.5 μmol/L),Taq DNA polymerase(1 U),and template DNA(1.5 ng/μL);The optimized anneal temperature was 46.8 ℃.Conclusion The established and optimized RAMP-PCR reaction system is stable and repeatable,which could provide the basis for the analysis of germplasm resources and genetic diversity of E.sinensis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.617
Threshold uncertainty score0.298

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.231
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it