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Record W2354374923

Cloning and Expression Analysis of a Wheat Chitinase Gene Wch2

2003· article· en· W2354374923 on OpenAlexaff
Liyan He

Bibliographic record

VenueActa Photophysiologica Sinica · 2003
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicStudies on Chitinases and Chitosanases
Canadian institutionsCAE (Canada)
Fundersnot available
KeywordsChitinaseStem rustBiologyGeneSignal peptideSouthern blotGene expressionMolecular biologySequence analysisCloning (programming)GeneticsPeptide sequence
DOInot available

Abstract

fetched live from OpenAlex

Using a wheat chitinase gene fragment derived from PCR as probe, a Chid1 chitinase gene, Wch2 , was isolated from a wheat genomic library. Sequence analysis indicated that Wch2 encodes a peptide of 311 amino acids with no intron, which contains a signal peptide, a cysteine-rich chitin-binding domain, two variable regions and two catalytic domains (Fig.1). Southern blot hybridization showed that there are multiple copies of Wch2 in wheat genome (Fig.2). Infection with stem rust fungus Puccinia graminis induced a differential expression of Wch2 in a pair of near-isogenic wheat lines (Fig.3). In resistant isogenic line Chinese Spring Sr11(CS-Sr11), an induction of Wch2 transcript was detected 3 days after inoculation and a massive increase of the expression was observed 6 days after incolation. In contrast, in susceptible line Chinese Spring sr11(CS-sr11), expression of the chitinase gene was not detected during the time courses assayed. Crude bacterial extracts of Wch2 expressed in E.coli showed a clear chitinase activity towards chitin(Fig.4). These results suggest that Wch2 may play an important role in the induced resistance responses to the stem rust fungus.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.050
Threshold uncertainty score0.600

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.254
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2003
Admission routes1
Has abstractyes

Explore more

Same venueActa Photophysiologica SinicaSame topicStudies on Chitinases and ChitosanasesFrench-language works237,207