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Record W2359751395 · doi:10.1177/205891581000100205

In Vitro Maturation of Human Immature Oocytes

2010· article· en· W2359751395 on OpenAlexaff
Jin‐Ho Lim, Ri‐Cheng Chian

Bibliographic record

VenueJournal of Reproductive and Stem Cell Biotechnology · 2010
Typearticle
Languageen
FieldMedicine
TopicReproductive Biology and Fertility
Canadian institutionsMcGill University
Fundersnot available
KeywordsOocyteAntral follicleIn vitro maturationInfertilityPregnancyAndrologyPregnancy ratePopulationFollicleMedicineGynecologyBiologyFollicular phaseEmbryoInternal medicine

Abstract

fetched live from OpenAlex

Ovarian stimulation regimes may be hazardous to a small proportion of women or may result in side effects. For such women IVM is recommended. IVM technology can be divided into two main approaches, namely (i) FSH and (ii) hCG priming. These two approaches improve oocyte maturation and pregnancy rates when the immature oocytes are retrieved from women with PCOS. Although the size of follicles appears to be important for subsequent embryonic development however the developmental competence of oocytes derived from the small antral follicles seems not to be adversely affected by the presence of a dominant follicle. In general, the clinical pregnancy and implantation rates per ET are now in the order of 35–40% and 10–15% respectively in women with PCOS following IVM. The combination of natural cycle IVF with immature oocyte retrieval followed by IVM is an attractive treatment alternative for women with various forms of infertility without recourse to ovarian stimulation. Natural cycle IVF/M together with IVM alone can be used to treat more than half of the population of infertile patients with acceptable pregnancy rate. Approximately 2,000 healthy infants have been born following immature oocyte retrieval and IVM.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0050.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.258
Teacher spread0.249 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2010
Admission routes1
Has abstractyes

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