Effect of flurbiprofen axetil on acute pain in patients with fracture of a variety of inflammatory mediators and pain score
Bibliographic record
Abstract
Objective To observe the effect of flurbiprofen axetil on plasma prostaglandin E2,5-HT,bradykinin,three kinds of inflammatory mediators and pain score before and after fracture patients with acute pain medication.Methods A total of 30 inpatients with acute pain caused by fracture were selected as research objects.The intravenous drip of nonsteroidal anti-inflammatory drugs and analgesic efficacy of flurbiprofen axetil injection were used for analgesia.Simplified the pain degree of patients before and after with the McGill pain score evaluation.Enzyme-linked immunosorbent assay(ELISA) nethod was used to determine plasma prostaglandin E2,5-HT,bradykinin before and after treatment.Results 30 min before the treatment the concentration of prostaglandin E2,5-HT,and bradykinin,and the short-form McGill pain questionnaire(MPQ) score were significantly higher than those of 2 h and 6 h after treatment(all P0.05).After 6 h,plasma prostaglandin E2,5-HT,bradykinin concentration were significantly higher than those after administration of 2 h(all P0.05).After administration of 6 h McGill pain score was higher than that 2 h after the treatment.Conclusions Flurbiprofen axetil can inhibit the fracture caused by acute pain in patients with prostaglandin E2,5-HT,bradykinin concentration in plasma and can effectively reduce the pain of patients.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".