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Record W2375250298 · doi:10.2310/6650.2005.00205.52

53 GENETIC DISCRIMINATION BY INSURERS AS A RESULT OF GENETIC RESEARCH AND TESTING: A COMPARISON OF NATIONAL POLICIES

2005· article· en· W2375250298 on OpenAlexaboutno aff
Robert J. Freishtat, Yann Joly, Denise Avard, M. Ellenberg, Bartha Maria Knoppers

Bibliographic record

VenueJournal of Investigative Medicine · 2005
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBRCA gene mutations in cancer
Canadian institutionsnot available
Fundersnot available
KeywordsGenetic testingGenetic discriminationActuarial scienceGeneticsBiologyBusiness

Abstract

fetched live from OpenAlex

<h3>Purpose</h3> Fear of discrimination by health and life insurers has been shown to deter individuals from participating in genetic research and testing. We aimed to construct a comparison of genetic discrimination policies in Canada, Australia, the United Kingdom, and the United States providing useful lessons regarding the management of genetic discrimination public policy. <h3>Methods</h3> MEDLINE and the HumGen database were searched for items related to genetic discrimination and health and/or life insurance. <h3>Results</h3> The Canadian, Australian, and UK health systems cover all citizens regardless of disease risk. However, life insurance applicants are not protected. In 2004, the Canadian Genetics and Life Insurance Task Force released a “Points to Consider Document” highlighting the importance of having a Canadian debate on the necessity of adopting a moratorium on the use of genetic test results for life insurance. In 2003, the Australian Law Reform Commission and the Australian Health Ethics Committee of the National Health and Medical Research Council recommended the adoption of a system consisting of a regulatory review aimed at ensuring that genetic information would be used in a scientifically reliable and actuarially sound manner. The Association of British Insurers9 Code of Practice, in 1999, mandated a “5-year moratorium on the use of genetic test results by insurers” up to a certain policy amount on life, long-term care and disability insurance. In 2001, the moratorium was strengthened and extended for an additional 5 years. As of 2004, 48 states and the District of Columbia had passed some form of legislation prohibiting genetic discrimination in health insurance decisions. At the federal level, The Genetic Information Non-discrimination Act (S. 1053) prohibits discrimination on the basis of genetic information regarding health insurance. It is now in the House of Representatives, where its outcome is uncertain. <h3>Conclusions</h3> The public9s concern about their own insurability necessitates action to ensure the successful conduct of future genetic epidemiological studies and testing. We argue that the adoption of a voluntary moratorium on genetic test results by the insurance industry appears to be the best option to answer both public anxiety and to provide a minimal amount of protection to insurance applicants.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.096
Threshold uncertainty score0.720

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.143
GPT teacher head0.422
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2005
Admission routes1
Has abstractyes

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