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Population Genomics Related to Adaptation in Elite Oat Germplasm

2016· article· en· W2381442710 on OpenAlexafffund
Kathy Esvelt Klos, Yung‐Fen Huang, Wubishet A. Bekele, D. E. Obert, Ebrahiem Babiker, Aaron D. Beattie, Åsmund Bjørnstad, J. M. Bonman, M. L. Carson, Shiaoman Chao, Belaghihalli N. Gnanesh, Irene Griffiths, Stephen A. Harrison, Catherine Howarth, Gongshe Hu, Amir M. H. Ibrahim, Emir Islamovic, Eric W. Jackson, Jean‐Luc Jannink, F. L. Kolb, Michael S. McMullen, J. Mitchell Fetch, J. Paul Murphy, H. W. Ohm, Howard W. Rines, B. G. Rossnagel, Jessica A. Schlueter, Mark E. Sorrells, Charlene P. Wight, Weikai Yan, Nicholas A. Tinker

Bibliographic record

VenueThe Plant Genome · 2016
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicWheat and Barley Genetics and Pathology
Canadian institutionsUniversity of SaskatchewanNational Association of Friendship CentresAgriculture Environmental Renewal Canada (Canada)
FundersAgriculture and Agri-Food CanadaBiotechnology and Biological Sciences Research CouncilU.S. Department of Agriculture
KeywordsBiologyGermplasmGenomicsEliteAdaptation (eye)Genomic selectionBiotechnologyPopulationPopulation genomicsEvolutionary biologyGeneticsGenomeAgronomyGenotypeSingle-nucleotide polymorphismGeneDemography

Abstract

fetched live from OpenAlex

Six hundred thirty five oat ( L.) lines and 4561 single-nucleotide polymorphism (SNP) loci were used to evaluate population structure, linkage disequilibrium (LD), and genotype-phenotype association with heading date. The first five principal components (PCs) accounted for 25.3% of genetic variation. Neither the eigenvalues of the first 25 PCs nor the cross-validation errors from = 1 to 20 model-based analyses suggested a structured population. However, the PC and = 2 model-based analyses supported clustering of lines on spring oat vs. southern United States origin, accounting for 16% of genetic variation ( < 0.0001). Single-locus -statistic () in the highest 1% of the distribution suggested linkage groups that may be differentiated between the two population subgroups. Population structure and kinship-corrected LD of = 0.10 was observed at an average pairwise distance of 0.44 cM (0.71 and 2.64 cM within spring and southern oat, respectively). On most linkage groups LD decay was slower within southern lines than within the spring lines. A notable exception was found on linkage group Mrg28, where LD decay was substantially slower in the spring subpopulation. It is speculated that this may be caused by a heterogeneous translocation event on this chromosome. Association with heading date was most consistent across location-years on linkage groups Mrg02, Mrg12, Mrg13, and Mrg24.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.202
Teacher spread0.177 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations81
Published2016
Admission routes2
Has abstractyes

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