Expression and significance of heat shock protein 70 in vascular cognitive impairment patients
Bibliographic record
Abstract
Objective:To explore the relationship between heat shock protein 70(HSP70) and vascular cognitive impairment(VCI). Methods:181 patients were divided into not cognitively impaired (NCI,n=52)and VCI (n=129) groups.Cognitive function and serum HSP70 levels in two groups were tested by Montreal Cognitive Assessment (MoCA) and enzyme linked immunosorbent assay (ELISA),respectively. Results:The serum HSP70 levels in the NCI and VCI groups were 11.29±2.66 ng / ml and 19.92±5.98 ng / ml, respectively,and there were significant differences (P 0.01).The correlation analysis revealed that the serum HSP70 levels were negatively correlated with the total MoCA scores (r=-0.742,P 0.01);Multivariable linear regression showed that the seium HSP70 levels were also negatively correlated with the memory scores,the visuospatial / executive scores and the orientation scores in the VCI groups. Conclusions:HSP70 may be used as the biochemical indicator for observing vascular cognitive impairment.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".