Effect of di-(2-ethylhexyl)-phthalate exposure on neurobehavioral and lipid peroxidation of mice
Bibliographic record
Abstract
To study the effect of DEHP on neurobehavioral(the ability of learning,memory and emotion) of Kunming mice and the oxidative damage caused by DEHP in their brain.Dividing twenty-four male kunming mice into 4 groups(n=6) randomly,including control group(Saline),low density DEHP treatment group(5 mg · kg-1 DEHP),medium density DEHP treatment group(50 mg · kg-1 DEHP) and high density DEHP treatment group(500mg/kg DEHP).To begin with,test the ability of learning and memory by Y-electric maze.Then,use the forced swimming and tail suspension tests to learn the depression of mice.Finally,the ROS level,and MDA contents of brain tissues were measured.According to the data,the ability of learning and memory of the three treatment groups are apparently lower than the control group,while their depression is extreme worse than control group(p0.05).What is more,comparing with the control group,the oxidative stress reactions of the three treatment groups are increasing significantly.The results suggest that DEHP does cause the oxidative damage in the mice's brains,which then results the abnormality of nervous behaviors.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".