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Record W2384742440

Analysis on polymorphism of paraoxonase 2 gene in Chinese Hainan Han healthy nationality

2007· article· en· W2384742440 on OpenAlexaboutno aff
Qian Shi

Bibliographic record

VenueJournal of Hainan Medical College · 2007
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicParaoxonase enzyme and polymorphisms
Canadian institutionsnot available
Fundersnot available
KeywordsGenotypeHan nationalityPolymorphism (computer science)GeneticsParaoxonaseNationalityMedicineChinaRestriction fragment length polymorphismGeneTraditional medicineEthnic groupDemographyBiologyInternal medicineGeographyImmigration
DOInot available

Abstract

fetched live from OpenAlex

Objective: In order to investigate the distribution of paraoxonase 2(PON2) gene polymorphism in Chinese Hainan Han nationality and provide a basis on the study of pathogeny of diseases associated with PON2.Methods: paraoxonase 2 genepolymorphism of 207 unrelated healthy individuals in Hainan was studied by means of polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP).Results: The PON2 gene polymorphisms(148 Ala/Gly and 311 Cys/Ser) were demonstrated,the frequencies were GG0.116、GA0.237、AA0.647、CC0.111、CS0.411、SS0.478 respectively.In Hainan Han nationality,the frequencies of the paraoxonase 2 genotype were significantly different in someone genotype(P0.05) with subjects of Taiwan,Scotland,England,Russia,Canada,African American,Caucasian American,or Australia.Conclusion: These results suggest that there are significant differences in the distribution of PON2 gene between Hainan Han nationality and other ethnic population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.113
Threshold uncertainty score0.621

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.303
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2007
Admission routes1
Has abstractyes

Explore more

Same venueJournal of Hainan Medical CollegeSame topicParaoxonase enzyme and polymorphismsFrench-language works237,207