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Record W2388038100

Distribution and drug resistance of Acinetobacter baumannii infection in patients with lung diseases

2012· article· en· W2388038100 on OpenAlexaff
Youyi Du, Lu Zhuqing, Debin Sun, Jiafeng Zhou, Xiong Xuefang

Bibliographic record

VenueZhongguo yiyuan ganranxue zazhi · 2012
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAntibiotic Resistance in Bacteria
Canadian institutionsCAE (Canada)
Fundersnot available
KeywordsCefoperazoneSulbactamMedicineSputumImipenemInternal medicinePiperacillinDrug resistanceAcinetobacter baumanniiCefepimeTazobactamMicrobiologyPneumoniaAntibioticsGastroenterologyTuberculosisAntibiotic resistanceBiologyPathologyPseudomonas aeruginosaBacteria
DOInot available

Abstract

fetched live from OpenAlex

OBJECTIVE To explore the distribution and drug susceptibility of Acinetobacter baumaanii in patients with lung diseases,so as to prevent the correlated infections.METHODS Routine bacterial identification for the submitted specimens in respiratory department from 2009 to 2010 was performed with ATB,the specimens infected with A.baumaanii were screened out,statistical analysis of A.baumaanii infections and the distribution of diseases was performed;the drug susceptibility testing for the isolates was carried out according to CLSI standards,the drug resistance was analyzed.RESULTS Totally 165 strains of A.baumaanii were isolated from 1020 specimens with the detection rate of 16.2%;the specimens mainly obtained from sputum,blood,secretions,urine and others,accounting for 57.6%,21.8%,11.5%,4.9%,and 4.2%,respectively,as compared with the sputum specimens,there were statistical significance(P0.01);A.baumaanii commonly distributed in the patients with ventilator-associated pneumonia,lung cancer,or tuberculosis,the difference between VAP and other diseases was statistically significant(P0.05);the result of drug susceptibility testing showed that A.baumaanii was susceptible to imipenem,cefoperazone/sulbactam,piperacillin/tazobactam,ofloxacin,cefepime,aztreonam,and piperacillin,and was resistant to the rest of antibiotics;the susceptibility rates to imipenem and cefoperazone/sulbactam were 52.7% and 38.8%,respectively,the difference in susceptibility rate was statistically significant as compared with other antibiotics(P0.05).CONCLUSION A.baumaanii isolates are with the highest detection rate from sputum specimens and are most common in the patients with VAP,the drug resistance rate is high,A.baumaanii isolates are relatively susceptible to imipenem and cefoperazone/sulbactam,according to drug susceptibility testing to enhance the therapeutic effect,so it is necessary to take a comprehensive consideration to improve the therapeutic effect on the basis of drug susceptibility testing.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.206
Teacher spread0.203 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2012
Admission routes1
Has abstractyes

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