Influence of Nicorandil and Trimetazidine on patients with recurrence of angina pectoris after percutaneous coronary intervention
Bibliographic record
Abstract
[Objective]To observe the therapeutic effect of Nicorandil and Trimetazidine on patients with recurrence of angina pectoris after percutaneous coronary intervention(PCI). [Methods]According to the criteria,150 patients were randomly and continuously collected from the Third Hospital of Xingtai City from October 2009 to July 2011,all patients received PCI and still had angina,and they were randomly divided into the Nicorandil group(75 cases) and the Trimetazidine group(75 cases).Two groups were given conventional secondary prevention drugs after PCI.On the basis of routine treatment,the Nicorandil group was treated with Nicorandil 10 mg by oral Administration,three times daily,and the Trimetazidine group was treated with Trimetazidine 20 mg by oral Administration,three times daily.The case numbers of angina pectoris,times and duration of angina attacks,classification of angina pectoris and the incidence rate of main adverse cardiovascular events(Mace) of patients within three months were observed.The Left ventricular ejection fraction(LVEF) of patients before medication and three months after medication were observed. [Results]The case numbers of angina pectoris,times of angina attacks and incidence rate of Ⅲ level angina pectoris(Canadian Cardiovascular Society) in the Nicorandil group were lower than those in the Trimetazidine group,the difference were significant(P0.05).The incidence rate of Mace in the Nicorandil group was lower than that in the Trimetazidine group,but the difference was not significant(P0.05).After three months of medication,the LVEF of the Nicorandil group and Nicorandil group had improved as compared with that before medication.After three months of medication,the LVEF of Nicorandil group was slightly higher than that of the Trimetazidine group,but the difference was not significant(P0.05). [Conclusion]On the basis of routine treatment,Nicorandil or Trimetazidine can reduce the times of heart attacks and improve the left ventricular function in patients with recurrence of angina pectoris after PCI.The effect of Nicorandil is better than that of Trimetazidine in alleviating angina pectoris.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".