Efficacy of fluoxetine in treatment of depression and functional rehabilitation in patients with acute cerebral infarction
Bibliographic record
Abstract
Objective To investigate the efficacy of fluoxetine in treating depression,motor dysfunction and cognitive dysfunction in the patients with acute cerebral infarction(ACI).Methods 186 patients with ACI hospitalized in our hospital from Jan 2012 to Dec 2012 were enrolled in this study and randomly assigned to the control group(n=93)and the observation group(n=93).The control group received the conventional therapy,including dehydration and reducing blood glucose.On the basis of the control group treatment,the observation group was given additional fluoxetine(20mg/d).The two groups were treated for 12 consecutive months.The depression status was evaluated by using the Hamilton Depression Scale(HAMD),the motor function was evaluated by using the National Institutes of Health Stroke Scale(NIHSS),and the cognitive function was evaluated by using the Montreal Cognitive Assessment Scale(MoCA).The scores were compared before and after treatment and between the two groups.Results The NIHSS scores after 3-month treatment in the two groups were significant declined compared with before treatment,the difference had statistical significance(P0.05),moreover the NIHSS scores after 3-,6-,12-month treatment in the observation group were significantly less than those in the control group,the differences between among groups had statistical significant(P0.05).The MoCA scores and the depression status in the control group had no statistical differences between before and after treatment(P0.05);while the MoCA scores after 3-months treatment in the observation group were increased than that before treatment(P0.05),and the depression status was improved to some extent(P0.05).Conclusion Adding fluoxetine on the basis of the conventional therapy could effectively relieve the depression status of the patients with ACI,improve their motor function and cognitive function,but it is needed to insist middle and long term medication.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".