Reliability and validity of Chinese version of Neuropsychiatric Inventory-Questionnaire in patients with Alzheimer' s disease
Bibliographic record
Abstract
Objective:To evaluate the reliability and validity of Chinese version of Neuropsychiatric Inventory-Questionnaire(NPI-Q).Methods:Fifty-one patients meeting criteria of probable Alzheimer' s disease(AD)of the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer' s disease and Related Disorders Association(NINCDS-ADRDA)were studied.All patients were drawn from database of Dementia Care and Research Center at Peking University Institute of Mental Health.Each subject was administered with the Mini-mental Status Examination(MMSE),Activities of Daily Living(ADL),Alzheimer' s disease Assessment Scale-Cognitive portion(ADAS-Cog),and Neuropsychiatric Inventory(NPI).The informants completed rating with NPI-Q.Sixteen subjects were retested at 3 months after initial assessment.Results:(1)Reliability.The coefficient of inter-item consistency(Cronbach' s α)was 0.851,and the Guttman split-half reliability was 0.825.The test-retest reliability of NPI-Q total score inter-rater reliability(ICC)was 0.860(P0.01),and test-retest reliability of NPI-Q total distress score ICC was 0.480(P0.05).(2)Validity.The item scores of severity of NPI-Q were correlated with each other(r=0.01~0.97),and with total score of NPI-Q significantly(r=0.33~0.87,P0.05).The item scores of distress of NPI-Q were correlated with each other(r=0.05~0.72),and with total score of distress significantly(r=0.47~0.90,P0.01).For all items,the scores of distress were correlated with scores of severity significantly(r=0.60~0.86,P0.01).The total score of NPI-Q severity was correlated with total score of distress(r=0.78,P0.01).The total score of NPI-Q severity was negatively associated with total score of MMSE(r=-0.39,P0.01),positively with total score of ADL,ADAS-cog,NPI and NPI-distress(r=0.47-0.82,P0.01).The total score of NPI-Q distress was negatively associated with that of MMSE(r=-0.32,P0.05),and positively correlated with ADL,ADAS-Cog,NPI,and NPI-distress (r=0.29~0.68,P0.05).NPI-Q consisted of three factors counting for 62.23% of variance,including psychosis,impaired affect and frontal function.Conclusion:The Chinese version of NPI-Q has good reliability and validity,worthy of extensive application.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".