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Record W2395395078 · doi:10.18192/riss-ijhs.v3i1.1448

Under-reporting of Adverse Drug Reactions: The Need for an Automated Reporting System

2013· article· en· W2395395078 on OpenAlexaffvenueabout
Benjamin R Pearson

Bibliographic record

VenueRevue interdisciplinaire des sciences de la santé - Interdisciplinary Journal of Health Sciences · 2013
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicPharmacovigilance and Adverse Drug Reactions
Canadian institutionsUniversity of Ottawa
Fundersnot available
KeywordsHealth carePharmacovigilanceDrug reactionHealth informaticsIgnoranceHealth professionalsMedicineInformaticsDrugAdverse drug reactionBusinessPublic healthNursingPolitical sciencePharmacology

Abstract

fetched live from OpenAlex

Although upwards of 32,000 adverse drug reactions are reported to Health Canada annually, this represents only approximately 5% of cases experienced by Canadians every year. This gross display of underreporting not only results in unrepresentative data in regards to adverse drug reactions, but further discredits databases used by healthcare professionals and in turn compromises the health and safety of Canadians. Major causes of underreporting seen in the literature are ignorance, diffidence and lethargy displayed by healthcare professionals. While Health Canada relies on these professionals to voluntarily report adverse drug reactions, the potential exists for an automated reporting system to remove causes of underreporting. Through integrating such a system with current health informatics technologies such as the electronic health record and utilizing existing health system communication technologies, healthcare professionals will be provided with representative data of adverse drug reactions in Canada and in turn be able to better serve their patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.033
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Science and technology studies
Consensus categoriesScience and technology studies
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.222
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0330.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0050.005
Scholarly communication0.0000.002
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.215
GPT teacher head0.563
Teacher spread0.347 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2013
Admission routes3
Has abstractyes

Explore more

Same venueRevue interdisciplinaire des sciences de la santé - Interdisciplinary Journal of Health SciencesSame topicPharmacovigilance and Adverse Drug ReactionsFrench-language works237,207