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Record W2408978226

The 2012 Interlaboratory Comparison of Forensic DNA Typing in Thailand

2014· article· en· W2408978226 on OpenAlexaff
Nonglak Sinkhan, Weawgarn Duangshatome, Wiparat Jaitrong, Kwanjai Kumyos, Rapeeporn Khienthong, Chalampoo Wongvoravivat, Tanin Bhoopat, Kanha Muisuk, Janpen Thanakitgosate, Chairat Manasatienkij, Kawin Rasmeepaisarn, Jintana Pradutkanchana, Suwit Rueangkittisakul, Budsaba Rerkamnuaychoke, Sukone Pradutkanchana

Bibliographic record

VenueDOAJ (DOAJ: Directory of Open Access Journals) · 2014
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicForensic and Genetic Research
Canadian institutionsRoyal Canadian Mounted Police
Fundersnot available
KeywordsMicrosatelliteForensic scienceTypingMitochondrial DNASTR analysisDNA profilingGeneticsBiologyForensic geneticsDNAGene
DOInot available

Abstract

fetched live from OpenAlex

Objective: To evaluate the results of the 2012 interlaboratory comparison for forensic deoxyribonucleic acid (DNA) typing including autosomal short tandem repeat loci (aSTR), Y-chromosome short tandem repeat loci (Y-STR), X-chromosome short tandem repeat loci (X-STR) and mitochondrial DNA (mtDNA). Material and Methods: The analysis was performed using 4 blood samples stored on FTA® cards. Twelve laboratories in Thailand participated in this study. The results from each participant were compared with the consensus results. Results: The analysis of aSTR, Y-STR, X-STR and mtDNA were performed in 12 (100.0%), 8 (66.7%), 6 (50.0%) and 7 (58.3%) laboratories, respectively. All DNA profiles of aSTR, Y-STR and X-STR from all the participating laboratories showed the same STR profiles. However, the calculation of forensic DNA typing statistical values and the format of laboratory reports among these laboratories showed several variations. Only the mtDNA test showed some variations among the laboratories. Conclusion: For aSTR, Y-STR and X-STR tests, the trainings in statistical calculation of forensic DNA typing are required. For mtDNA test, workshop training should be established. Furthermore, a standard guideline for forensic DNA typing reports should be released in order to provide all the necessary information in the laboratory reports.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.039
metaresearch head score (Gemma)0.037
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.039
Threshold uncertainty score0.204

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0390.037
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0040.003
Science and technology studies0.0010.001
Scholarly communication0.0030.001
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.145
GPT teacher head0.533
Teacher spread0.388 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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Same venueDOAJ (DOAJ: Directory of Open Access Journals)Same topicForensic and Genetic ResearchFrench-language works237,207