[Factors associated with mitral regurgitation in men with ischemic heart disease without myocardial infarction].
Bibliographic record
Abstract
UNLABELLED: Being independent predictor of cardiovascular mortality, mitral regurgitation (MR) has a negative influence on prognosis of ischemic heart disease (IHD) patients. Data on MR pathogenesis in IHD patients without myocardial infarction (MI) are insufficient. PURPOSE: To reveal factors associated with MR in CAD men without myocardial infarction. METHODS: Out of 16839 patients of the "Register of performed coronary angiography" we selected men with significant coronary stenosis (> or = 75% of lumen of at least one epicardial artery) who had no acute or previous MI: 1001 patients without MR and 66 patients with moderate and severe MR. RESULTS: Men with MR were older (59.0 +/- 7.3 vs 52.8 +/- 7.4 year), more often had NYHA class III--IV heart failure (27.4 vs. 10.9%), arrhythmias (61.0 vs. 14.8%) (all p < 0.001), but rate of angina of Canadian Cardiovascular Society (CCS) class III--IV was lower among patients with MR (46.7 vs. 63.2%, p = 0.019). Echocardiographic index of left atrial dimension was higher in men with MR (23.5 +/- 2.9 vs. 20.3 +/- 2.1 mm/m2, p < 0.001) as well as all indices of linear echocardiographic dimensions of cardiac chambers; left ventricular (LV) ejection fraction was lower (51.0 +/- 10.7 vs 61.0 +/- 4.9%, p < 0.001) in this group. There were no differences in coronary angiographic data between groups. According to the mulrivariate analysis, MR was independently associated with arrhythmias (odds ratio [OR] 7.92; 95% confidence interval [CI] 3.21-19.57; p < 0.001), index of left atrial dimension (OR = 1.25; 95% CI 1.09-1.43; p = 0.002), LV ejection fraction (OR = 0.49; 95% CI 0.75-0.89; p < 0.001), CCS angina class (OR = 0.49; 95%CI 0.24-0.98; p = 0.044) and age (OR = 1.09; 95%CI 1.03-1.16; p = 0.005). MR in CAD men without MI was associated with arrhythmias, higher index of left atrium dimension, lower LV ejection fraction, worse CCS angina class and older age. No association between MR and localization of significant coronary lesions was found.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".