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Record W2412438638

Cardiac revascularization: CABG vs. PTCA.

2009· letter· en· W2412438638 on OpenAlexaboutno aff
Faran Polani, Syed Muhammad Ali Saad

Bibliographic record

VenuePubMed · 2009
Typeletter
Languageen
FieldMedicine
TopicCoronary Interventions and Diagnostics
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineCardiologyInternal medicineCoronary artery diseaseMyocardial infarctionRevascularizationStenosisArteryAngioplasty
DOInot available

Abstract

fetched live from OpenAlex

Madam, Coronary artery disease (CAD) is the leading cause of all the cardiovascular related morbidities and mortalities worldwide. As many as 4.5 million people in the developing world die of CAD each year. South Asians have the highest susceptibility to atherosclerosis making them most vulnerable to CAD related mortalities worldwide.1 Coronary Artery Bypass Grafting (CABG) and Per Cutaneous Transluminal Coronary Angioplasty (PTCA) though invasive, are by all means more effective and superior to the conventional medical therapy for the management of Myocardial Infarction (MI) patients. Primary PTCA is an emergency measure for the management of acute MI whereas CABG being a surgical procedure requires extensive pre operative preparation and cannot be used as a measure for acute management of MI. Over the years many randomized trials have been carried out around the world indicating the long-term survival rates of both CABG and PTCA depending upon the anatomical site and extent of the disease. Although 20 year survival of CABG and PTCA is the same, the 3 year survival rate for patients undergoing PTCA for a single vessel CAD with no or insignificant (less than 70%) LAD blockage has been 2.9% better than those undergoing CABG. On the contrary, CABG proved superior to PTCA in terms of the 3 year survival rate of patients having either three vessels CAD or proximal LAD stenosis of more than 70%.2 CABG being the more invasive procedure has longer recovery period, however, it is still the treatment of choice for patients requiring simultaneous valvular replacement. A study carried out in United States and Canada demonstrated that as many as 54 % of patients undergoing PTCA had at least one re-hospitalization in 5 years after the initial procedure compared to only 8 % re-hospitalization in patients who had undergone CABG over the same period.3 The primary cost of CABG has been reported to be 53% higher than PTCA, however, the gap closes down to less than 5 % during the first two years due to the post-treatment morbidity associated with PTCA.4 In the setting of restenosis following PTCA in small vessels, diffuse narrowing and diabetes, drug eluting stents are being used with favorable results.5 As a result of this in the recent past, there has been a significant change in clinical management of patients from surgical to percutaneous revascularization.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.022
Threshold uncertainty score0.072

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0220.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.234
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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