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Record W2413577533 · doi:10.3928/15428877-20060501-01

Photodynamic Therapy in Young Patients

2006· article· en· W2413577533 on OpenAlex
Andrew Lam, Henry Lee, Allen C. Ho, Carl D. Regillo, J. Arch McNamara, Mitchell D Fineman

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueOphthalmic surgery, lasers & imaging retina · 2006
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicDermatological and Skeletal Disorders
Canadian institutionsnot available
Fundersnot available
KeywordsPhotodynamic therapyMedicineChemistry

Abstract

fetched live from OpenAlex

<H4>BACKGROUND AND OBJECTIVE</H4> <P>To present a consecutive case series of patients 50 years or younger who underwent photodynamic therapy (PDT) for choroidal neovascularization (CNV) from etiologies other than age-related macular degeneration.</P> <H4>PATIENTS AND METHODS</H4> <P>Retrospective chart review of 35 consecutive eyes of 34 patients.</P> <H4>RESULTS</H4> <P>Visual acuity remained stable or improved in 20 of 35 eyes. Thirteen eyes with myopic degeneration had pre-treatment and post-treatment mean visual acuities of 20/100 and 20/200, respectively. Eight eyes with idiopathic CNV had an improvement of mean visual acuity from 20/200 to 20/125. Six eyes with ocular histoplasmosis displayed a stable mean visual acuity of 20/50. Of 3 eyes with angioid streaks, visual acuity remained stable in 2 eyes and declined in 1 eye. Five eyes with other etiologies all had improved vision.</P> <H4>CONCLUSION</H4> <P>Although the current literature shows evidence that PDT is beneficial in treating CNV secondary to myopic degeneration, the evidence for etiologies such as idiopathic causes, ocular histoplasmosis, and angioid streaks is optimistic but remains unproven. Our study suggests that PDT may be beneficial in stabilizing and improving vision when treating CNV from these etiologies.</P> <P>[<CITE>Ophthalmic Surg Lasers Imaging</CITE> 2006;37:182-189.]</P> <H4>AUTHORS </H4> <P>From the Retina Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.</P> <P>Accepted for publication February 26, 2006.</P> <P>Presented at the 23rd Annual Meeting of the American Society of Retina Specialists in Montreal, Quebec, Canada, July 16-20, 2005.</P> <P>Address reprint requests to Allen C. Ho, MD, Retinovitreous Associates, 910 East Willow Grove Ave., Wyndmoor, PA 19038.</P>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.853

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.212
Teacher spread0.208 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it