“Tinkle Tinkle Little Girl, How We Wonder Why You Can’t”: An Unusual AIDP-like Syndrome in a Toddler
Bibliographic record
Abstract
Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) is most frequently associated with rapidly progressive flaccid paralysis and areflexia.The estimated childhood incidence of AIDP (0-15 years of age) is 0.34 to 1.34 per 100,000 per year and the diagnosis of AIDP is often delayed in up to 2/3 of preschool age children due to nonspecific clinical symptoms and intrinsic difficulties in performing neurological examinations in this age group. 1 Further contributing to diagnostic inaccuracy is the presence of AIDP variants such as Miller-Fisher syndrome and the pharyngeal-cervical-brachial variant.The major concern with such phenotypic variations is that misdiagnosis or delay in treatment can have substantial effects on acute mortality and chronic morbidity.1 We report a case of a three year-old previously healthy girl with a purely autonomic variant of an AIDP-like syndrome consisting only of urinary and stool retention with nerve root enhancement with normal strength, (CSF) and nerve conduction studies responsive to intravenous immunoglobulin (IVIG) treatment.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.002 | 0.002 |
| Scholarly communication | 0.001 | 0.002 |
| Open science | 0.002 | 0.002 |
| Research integrity | 0.003 | 0.004 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".