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Record W2416887251

Carotid sinus pressure changes during push-pull maneuvers.

2006· article· en· W2416887251 on OpenAlexaff
Len Goodman, Liza Grosman‐Rimon, Romuald Mikuliszyn

Bibliographic record

VenuePubMed · 2006
Typearticle
Languageen
FieldMedicine
TopicHeart Rate Variability and Autonomic Control
Canadian institutionsDefence Research and Development Canada
Fundersnot available
KeywordsChemistryCentrifugeAnimal scienceInternal medicineCardiologyMedicinePhysicsBiology
DOInot available

Abstract

fetched live from OpenAlex

INTRODUCTION: The push-pull maneuver (PPM) is defined as a reduction in G-tolerance when positive acceleration (+Gz) immediately follows negative acceleration (-Gz) exposure, with the carotid baroreceptors presumably playing a dominant role in the ensuing BP (SBP) responses. The objective of this study was to determine whether application of neck pressure (NP) during the preceding -Gz phase maintains +Gz tolerance during subsequent +Gz. METHODS: There were 10 experienced men who were exposed to 3 centrifuge run types using a multi-axis centrifuge: a relaxed control run from +1.4 baseline to visual tolerance; a relaxed control PPM run (PPM-C) consisting of 5 s of -1 Gz followed by 15 s of +Gz to visual tolerance; and an experimental PPM run performed with pressurized neck (PPM-NP) consisting of -1 Gz for 5 s followed by 15 s of +Gz at the previous PPM-C G-tolerance level. RESULTS: Relaxed control G tolerance (3.6 _ 0.26 Gz) was greater vs. the PPM-C (3.0 +/- 0.21 Gz) and PPM-NP (3.1 +/- 0.20 Gz) conditions, but the two PPM conditions did not differ significantly. During -Gz, mean R-R interval for PPM-NP was significantly shorter than in the PPM-C from second 1 to second 3. During the +Gz phase, however, R-R interval responses between PPM-C and PPM-NP differed only at seconds 8 and 9. There were no differences in carotid sinus SBP between PPM-C and PPM-NP during -Gr. During +Gz, carotid sinus SBP was significantly depressed in PPM-NP and PPM-C conditions vs. Control. DISCUSSION: Application of NP during the -Gz phase, despite altering R-R interval, did not ameliorate SBP responses or reductions in G tolerance during subsequent +Gz exposure. Despite neck compression counteracting increased carotid hydrostatic pressure during -Gz, the carotid baroreceptor response is likely opposed by the aortic or other baroreceptors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.402
Threshold uncertainty score0.496

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.193
Teacher spread0.181 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2006
Admission routes1
Has abstractyes

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