Etude phytochimique et biologique des trois Alphitonia (Rhamnaceae) endémiques à la Nouvelle-Calédonie.
Bibliographic record
Abstract
Ce travail est consacre a l'etude phytochimique des feuilles, branches et des ecorces de tronc d'Alphitonia xerocarpa et Alphitonia erubescens, ainsi que celle des fruits d'Alphitonia neocaledonica. Cette etude a permis d'isoler et d'identifier 48 composes dont 23 correspondent a de nouvelles molecules. Les composes isoles peuvent etre classes en sept groupes : 2 sterols dont un glycosyles, 10 triterpenes, 19 saponosides, 12 flavonoides, un lignane glycosyle, trois glycosides phenoliques, et un nucleoside. La determination structurale des composes isoles a ete realisee a l'aide des techniques spectroscopiques de RMN 1D & 2D et par la spectrometrie de masse ESI-MS.L'evaluation de l'activite anti-oxydante effectuee sur les differents extraits obtenus a montre une bonne activite des extraits hydro-alcooliques, seul l'extrait butanolique des fruits d'A. neocaledonica a donne une activite anti-tyrosinase interessante dans le domaine dermato-cosmetique.Les tests biologiques menes en bacteriologie et en toxicologie cellulaire a conduit a l'identification des composes ayant des activites importantes antibacterienne contre deux bacteries a Gram positif (CMI [4-32 µg/ml]) et antiproliferative contre les cellules KB (CI50 [2,6-7,9 µM/ml]).Ces plantes pourraient donc etre une nouvelle source d'exploitation durable neo-caledonienne dans le secteur de l'industrie cosmetique ou/et pharmaceutique, car les composes actifs sont des produits majoritaires provenant des matieres vegetales regenerables (feuilles, branches et fruits).
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".