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Record W2428024166 · doi:10.2967/jnumed.116.172346

Evaluation of Apoptosis with <sup>99m</sup>Tc-rhAnnexin V-128 and Inflammation with <sup>18</sup>F-FDG in a Low-Dose Irradiation Model of Atherosclerosis in Apolipoprotein E–Deficient Mice

2016· article· en· W2428024166 on OpenAlexaff
Maryam Kamkar, Lihui Wei, Chantal Gaudet, Michelle Bugden, Julia Petryk, Yin Duan, R. Glenn Wells, Yves L. Marcel, Nicholas D. Priest, Ronald E. J. Mitchel, Terrence D. Ruddy

Bibliographic record

VenueJournal of Nuclear Medicine · 2016
Typearticle
Languageen
FieldImmunology and Microbiology
TopicBiomarkers in Disease Mechanisms
Canadian institutionsNordion (Canada)Canadian Nuclear LaboratoriesUniversity of Ottawa
Fundersnot available
KeywordsInflammationApoptosisChemistryAntibodyCD68Apolipoprotein ENuclear medicinePathologyMedicineEndocrinologyInternal medicineImmunologyImmunohistochemistryBiochemistry

Abstract

fetched live from OpenAlex

Tc-rhAnnexin V-128 at 3 time points. METHODS: Tc-rhAnnexin V-128) were determined with digital autoradiography. Aortic sinus sections were stained with Sudan IV for assessment of lesion area and stage, antiCD68 antibody for inflammation and anti-cleaved-caspase 3 antibody for apoptosis. RESULTS: Tc-rhAnnexin V-128, or no radiotracer). CONCLUSION: mice treated with low-dose radiation. Advanced lesions are characterized by increased apoptosis and either less or similar amounts of inflammation, shown on immunohistochemistry and autoradiography. Treatment with radiotracers had no significant effects on extent of atherosclerosis, inflammation, or apoptosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.683
Threshold uncertainty score0.553

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.241
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2016
Admission routes1
Has abstractyes

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