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Record W2437837530 · doi:10.1017/cjn.2016.134

P.029 Case report: Facial diplegia and aseptic meningitis in a 44 year-old man returning from Côte d’Ivoire

2016· article· en· W2437837530 on OpenAlexvenueno aff
HA AlDhukair, R. Peter Altman, A G Parks, MP Cheng, A Damian

Bibliographic record

VenueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · 2016
Typearticle
Languageen
FieldMedicine
TopicFacial Nerve Paralysis Treatment and Research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineAseptic meningitisSeroconversionPediatricsCSF pleocytosisViral meningitisInternal medicineMeningitisSurgeryImmunologyAntibody

Abstract

fetched live from OpenAlex

Background: Bilateral facial paralysis is a rare manifestation of Human Immunodeficiency Virus (HIV). Few cases of HIV seroconversion syndrome presenting with aseptic meningitis and facial diplegia have been previously reported. Methods: Case Report. Case Description: A 44-year-old male with uncontrolled hypertension who presented with 5-day history of migrainous headache, bucco-labial dysarthria, meningismus and dysguesia. Three weeks prior to presentation, he suffered a transient febrile illness preceded by an unprotected sexual encounter while vacationing in Côte d’Ivoire. Examination was significant for hypertensive urgency, bilateral lower motor neuron (LMN) facial paralysis, and meningeal irritation. Investigations revealed acute on chronic renal impairment and left ventricular hypertrophy. Brain MRI (without contrast) revealed microhemorrhages with dystrophic calcifications and microangiopathic changes. CSF analysis revealed 55 WBC (lymphocytic), normal glucose, and 0.67g/L protein. The infectious work-up was positive for HIV, which was confirmed by Western Blot (WB). CD4 count was 176 cells/μL and the viral load was 419,289 copies/ml. Lyme antibodies were also positive by enzyme-linked immunosorbent assay (ELISA), but negative by WB. Discussion: Facial diplegia is a rare manifestation of HIV, and can be indicative of a seroconversion syndrome. This case illustrates another layer of complexity; deciphering acute from chronic systemic manifestations of hypertension, and appreciating falsely positive Lyme antibodies by ELISA during acute HIV seroconversion.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesScience and technology studies
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.235
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.005
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.303
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes1
Has abstractyes

Explore more

Same venueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences NeurologiquesSame topicFacial Nerve Paralysis Treatment and ResearchFrench-language works237,207