Human chorionic gonadotropin for in vitro oocyte maturation: does it improve the endometrium or implantation?
Bibliographic record
Abstract
OBJECTIVE: To determine the effect of human chorionic gonadotropin (hCG) priming on endometrial receptivity in women with polycystic ovary syndrome undergoing in vitro maturation. STUDY DESIGN: The study was a randomized, controlled trial. After a withdrawal bleed, on day 8-10 of the cycle, women were randomized to receive 10,000 IU hCG or none 36 hours before immature oocyte retrieval. Oocytes were matured and fertilized, and up to 3 embryos were transferred. Prior to transfer, endometrial thickness, uterine artery pulsatility index and subendometrial bloodflow were determined. RESULTS: There was no difference in endometrial thickness (10.1 vs. 10.4 mm), uterine artery pulsatility index (2.45 vs. 2.65) or absent subendometrial bloodflow (23% vs. 18%) between the treatment and control groups. Higher numbers of embryos were produced in the treatment group (7.0 vs. 3.6), resulting in more pregnancies, although the implantation rates (16.7 vs. 16.0%) were similar. CONCLUSION: Preretrieval hCG priming does not improve the ultrasound parameters of endometrial receptivity or the implantation rate, although more embryos are generated.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".