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The genetic architecture of type 2 diabetes

2016· article· en· 1,112 citations· W2461793432 on OpenAlex· 10.1038/nature18642

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.004
GPT teacher head0.237
Teacher spread
0.233 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature
Topic
Genetic Associations and Epidemiology
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
McGill University Health CentreMcGill UniversityMcGill University and Génome Québec Innovation Centre
Funders
National Institute on Minority Health and Health DisparitiesNational Institute of Diabetes and Digestive and Kidney DiseasesNational Institute of Mental HealthNational Heart, Lung, and Blood InstituteNovo Nordisk FondenMedical Research CouncilNational Institute of General Medical SciencesNational Institute for Health and Care ResearchNovo NordiskCanadian Institutes of Health ResearchNational Institutes of HealthLundbeckfondenNational Cancer InstituteBritish Heart FoundationNational Human Genome Research InstituteWellcome TrustNational Institute on AgingBristol-Myers Squibb
Keywords
Genetic associationGeneticsGenetic architectureBiologyGenome-wide association studyGenotypingExomeType 2 diabetesExome sequencingMinor allele frequencyImputation (statistics)HeritabilityDNA sequencingMissing heritability problemWhole genome sequencingAllele frequencySingle-nucleotide polymorphismGenomeAlleleGeneQuantitative trait locusMutationGenotypeDiabetes mellitusMissing data
Has abstract in OpenAlex
no