Simple Engineering of Polymer–Nanoparticle Hybrid Nanocapsules
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Abstract A general method to generate hybrid hollow capsules is reported. The process is based on the stabilization of solvent droplets by nanoparticles, in macroscopically miscible mixtures of tetrahydrofuran (THF) and water. After addition of a crosslinking polymer and removal of the solvent core, capsules of diameter ca 100 nm are obtained. This novel strategy does not require the use of block copolymers. In contrast, most methods reporting the formation of hybrid nanocapsules incorporate nanoparticles into block‐copolymer polymersomes or use nanoparticles tethered with block‐copolymers. The nanocapsules were characterized using a full set of techniques including nanoparticle tracking analysis, electron microscopy and liquid phase atomic force microscopy. Our results show that the vesicular shape of the nanocapsules is templated by the liquid droplets. Nanocapsules were prepared from quantum dots, gold nanoparticles, superparamagnetic iron oxide nanoparticles and mixtures of particles. The entrapment of a fluorescent dye was also demonstrated. Thus, nanocapsules with dual properties (e.g., magnetic and fluorescent) are easily obtained. Interestingly, the magnetic nanocapsules enable magnetic resonance imaging contrast enhancement of tumors in vivo.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it