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Record W2465274096 · doi:10.1118/1.4955547

SU‐C‐201‐07: Towards Clinical Cherenkov Emission Dosimetry: Stopping Power‐To‐Cherenkov Power Ratios and Beam Quality Specification of Clinical Electron Beams

2016· article· en· W2465274096 on OpenAlexaff
Yana Zlateva, Jan Seuntjens

Bibliographic record

VenueMedical Physics · 2016
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsMcGill University
Fundersnot available
KeywordsCherenkov radiationPhysicsDosimetryTruebeamBeam (structure)Stopping powerMonte Carlo methodLaser beam qualityLinear particle acceleratorPhotonElectronNuclear physicsIonization chamberCathode rayAtomic physicsOpticsComputational physicsIonizationNuclear medicineIonDetector

Abstract

fetched live from OpenAlex

Purpose: We propose a Cherenkov emission (CE)‐based reference dosimetry method, which in contrast to ionization chamber‐based dosimetry, employs spectrum‐averaged electron restricted mass collision stopping power‐to‐Cherenkov power ratios (SCRs), and we examine Monte Carlo‐calculated SCRs and beam quality specification of clinical electron beams. Methods: The EGSnrc user code SPRRZnrc was modified to compute SCRs instead of stopping‐power ratios (single medium: water; cut‐off: CE threshold (observing Spencer‐Attix conditions); CE power: Frank‐Tamm). SCRs are calculated with BEAMnrc for realistic electron beams with nominal energies of 6–22 MeV from three Varian accelerators (TrueBeam Clinac 21EX, Clinac 2100C/D) and for mono‐energetic beams of energies equal to the mean electron energy at the water surface. Sources of deviation between clinical and mono‐energetic SCRs are analyzed quantitatively. A universal fit for the beam‐quality index R50 in terms of the depth of 50% CE C50 is carried out. Results: SCRs at reference depth are overestimated by mono‐energetic values by up to 0.2% for a 6‐MeV beam and underestimated by up to 2.3% for a 22‐MeV beam. The variation is mainly due to the clinical beam spectrum and photon contamination. Beam angular spread has a small effect across all depths and energies. The influence of the electron spectrum becomes increasingly significant at large depths, while at shallow depths and high beam energies photon contamination is predominant (up to 2.0%). The universal data fit reveals a strong linear correlation between R50 and C50 (ρ > 0.99999). Conclusion: CE is inherent to radiotherapy beams and can be detected outside the beam with available optical technologies, which makes it an ideal candidate for out‐of‐beam high‐resolution 3D dosimetry. Successful clinical implementation of CE dosimetry hinges on the development of robust protocols for converting measured CE to radiation dose. Our findings constitute a key step towards clinical CE dosimetry.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.006
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.422
Teacher spread0.373 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2016
Admission routes1
Has abstractyes

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