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Record W2465842628 · doi:10.5897/ajb11.2096

Molecular cloning and characterization of the chalcone isomerase gene from sweetpotato

2011· article· en· W2465842628 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAFRICAN JOURNAL OF BIOTECHNOLOGY · 2011
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicPlant Virus Research Studies
Canadian institutionsMcGill University
FundersChina Scholarship CouncilNational Natural Science Foundation of China
KeywordsChalcone isomeraseChalconeChalcone synthaseBiochemistryAnthocyaninGeneBiologyIsomeraseChemistryBiosynthesisBotanyStereochemistry

Abstract

fetched live from OpenAlex

Anthocyanins are flavonoids and possess extensive bioactivities and pharmacological properties. Chalcone isomerase (CHI; EC 5.5.1.6) is an essential enzyme of the anthocyanins biosynthetic pathway, which catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. In order to investigate the role of chalcone isomerase in anthocyanins biosynthesis in sweetpotato, we cloned and characterized the chalcone isomerase gene from purple-fleshed sweetpotato (Ipomoea batatas (L.) Lam) cultivar Yuzi 263, which was designated as IbCHI (Genbank accession number: JN083840). The full-length cDNA of IbCHI was 890-bp long and contained a 732-bp coding sequence encoding a polypeptide of 243-amino acids. A phylogenetic tree of CHIs was constructed from different organisms including plants and algae, which showed that IbCHI had high similarities with other plant CHIs. Tissue expression pattern analysis indicated that IbCHI was expressed constitutively in all sweetpotato tissues including roots, stems, young leaves, old leaves and petiole with highest expression in roots, and at the same time the anthocyanin content in the tissues coincided with the gene expression pattern. The cloning and characterization of IbCHI will be helpful in the understanding of the role of CHI involved in the anthocyanins biosynthesis at the molecular level and provide a candidate gene for metabolic engineering of the anthocyanins biosynthesis in sweetpotato.   Key words: Purple-fleshed sweetpotato, chalcone isomerase, anthocyanin, expression profile.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.059
Threshold uncertainty score0.089

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.203
Teacher spread0.180 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it