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Record W2477174374

Diflubenzurone toxicity upon the planarian Dugesia tigrina (Girard)

2003· article· en· W2477174374 on OpenAlexaboutno aff
Mirjana Kalafatić, Goran Kovačević, Irina Župan, Damjan Franjević

Bibliographic record

VenuePeriodicum Biologorum · 2003
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPlanarian Biology and Electrostimulation
Canadian institutionsnot available
Fundersnot available
KeywordsPlanarianBiologyRegeneration (biology)BlastemaAnatomyPlanariaZoologyAndrologyCell biologyMedicine
DOInot available

Abstract

fetched live from OpenAlex

Background and purpose: The main aim of this study was to determine the effect of low doses of insecticide diflubenzurone on the Dugesia tigrina (Gir.) species in laboratory conditions. Materials and methods: Individuals of planarian Dugesia tigrina (Gir.) were treated with 0.02 % and 0.01 % water solution of insecticide diflubenzurone for 24 hours. Mortality and behavioral, morphological, cytological and histological changes were monitored, as well as regeneration and the course of recovery. Morphological changes and behaviour were monitored daily by means of stereomicroscope. For cytological and histological analysis, on the 1st, 2nd, 3rd, 6th and 11th day after the treatment two extremely damaged animals from each concentration were fixed, embedded into paraplast, cut, stained and immerse into Canada balsam. Results: Treatment with water solution of diflubenzurone resulted with mortality in the higher concentration. It also caused behavioural changes and extreme morphological, histological and histological damages. Anterior parts of planarian body were extremely damaged, but recovered successfully. In this part of the body greater amount of neoblasts and nerve tissue was present. After regenerative processes on the posterior part of the body certain lower number of permanent deformations was remarked. Less damaged planarians regenerated after the short period of time, but strongly damaged animals needed longer period for recovery. It took nine days for the complete regeneration of the damaged body parts. Conclusions: Used concentrations of diflubenzurone caused mortality, behavioral changes, as well as cytological and histolgical changes in treated planarians. Reticular cells and neoblasts take part in the formation of regeneration blastema. Results showed that the anterior parts of planarian body were more sensitive to diflubenzurone treatment than the posterior, but anterior parts regenerated faster and more successfully. After the regenerative processes, small amount of permanent deformations on the posterior parts of the body was established.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.703
Threshold uncertainty score0.644

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.218
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2003
Admission routes1
Has abstractyes

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