Amniotic Membrane as Allograft for Construction of Neovagina by McIndoe Technique in Vaginal Agenesis
Bibliographic record
Abstract
BACKGROUND: To assess the anatomical and functional results of neovagina creation with amniotic membrane. METHODS: We operated on three young women with vaginal agenesis two of whom had a diagnosis of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and the other mixed gonadal dysgenesis. The mean age was 29.67 years (range 28-33). A fresh amniotic membrane retrieved from a Cesarean section on the same operation date was prepared over a mould and inserted into the newly formed tunnel between the bladder and the rectum as per McIndoe technique. The patients were followed up for one year minimum. RESULTS: Mean vaginal depth achieved was 8, 10 and 7 cm (average 8.3 cm) at the 12 month follow-up clinic. Two patients expressed having satisfactory sexual life at follow-up interview. One patient who had infrequent coitus and neglected appropriate use of mould needed further follow-up in clinic and self-dilation. CONCLUSİONS: McIndoe vaginoplasty with fresh-homologous amniotic membrane is an effective low-risk procedure. It can produce good results in fairly short time span with modest demand on patient compliance and rare morbidity.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".