Abstract 18838: The Impacts of Burst Exercise Compared to Sustained Exercise on the Cardiometabolic Status and Exercise Behavior of Newly Diagnosed Type 2 Diabetic Patients
Bibliographic record
Abstract
Introduction: Physical activity is an integral part of type 2 diabetes (NIDDM) rehabilitation. Historically, NIDDM rehabilitation has employed low intensity, sustained exercise. Recent studies have demonstrated cardiometabolic benefits of high intensity burst exercise in healthy volunteers. The impacts of burst exercise in NIDDM have yet to be assessed. This study compared the impacts of burst and sustained exercises on cardiometabolic factors including: BMI, exercise adherence, cardiopulmonary fitness, HbA1C and lipid profiles in newly diagnosed NIDDM. Hypothesis: High-intensity burst physical activity may yield greater cardiometabolic benefits than low intensity, sustained exercise. Methods: This was a single center, single blind randomized trial. 76 patients, within three months of diagnosis of NIDDM, were recruited. Patients were randomized to a control group prescribed 30 minutes of exercise five days a week at 65% of target heart rate or an intervention group prescribed ten minutes of exercise three times a day, five days a week at 85% of target heart rate. All patients underwent routine blood tests, stress tests and logged exercise duration and frequency in logbooks. Patients were excluded from the study if they had evidence for diabetic end organ damage or cardiovascular disease, or took medications which would impact the cardiometabolic parameters assessed in this study. Results: Of 225 patients screened, 76 patients were recruited for the study with an average age of 67; 70% were male. No significant differences in demographics were noted between groups. Patients prescribed the burst regimen exercised 27% more than the control (p<0.01). Burst exercise patients also showed a 2.3 fold greater improvement in HbA1c (p<0.01). The intervention group also improved more in their lipid profile, BMI and cardiopulmonary fitness (as measured by stress testing). Linear regression analysis revealed greater improvements in both HbA1C and BMI with burst exercise than with sustained exercise, for the same duration of exercise. Conclusions: The burst exercise regimen significantly improved the cardiometabolic and fitness status of newly diagnosed NIDDM. This regimen may represent a simple and effective way to improve diabetes rehabilitation.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.009 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".