205: Cervical Cancer Brachytherapy in Canada: A Focus on Interstitial Brachytherapy Utilization
Bibliographic record
Abstract
below the superior and inferior extents of the target volume.For patients that received planning CT scans both immediately before and after rectal tube insertion, treatment plans were generated retrospectively with matched rectal D2cc.The resulting plans were compared visually, and the dose received by the HR-CTV D90 was compared.Results: All patients were treated with a combination of external beam radiotherapy to the pelvis and 3-5 fractions of high-dose rate interstitial brachytherapy in twice daily fractions.Ten and 19 patients were treated without and with a rectal tube respectively.Rectal volume between the first and third fractions was significantly more reproducible in the rectal tube group (p = 0.038).There was a significant increase in the HRCTV D90 with the use of a rectal tube (mean HRCTV D90 99.5% in the non-rectal tube group and 106% in the rectal tube group, p = 0.002).There was no significant difference in the D2cc rectum between the two groups (p = 0.77).Seven patients received a planning CT immediately prior to and immediately after rectal tube insertion, and plans with matched rectal doses were generated (11 pairs of plans).For these patients there was no significant difference in the HRCTV D90 between the rectal tube and no rectal tube plans (p = 0.187).There were seven plans in which the use of a rectal tube increased the HRCTV D90, and four plans in which it lowered the HRCTV D90.On visual inspection of these plans the rectal tube appeared to push the rectal wall anteriorly.Conclusions: For the patients included in this study, the use of a rectal tube in ISBT significantly reduced variability in rectal volume between the first and third treatment fractions.Overall the use of a rectal tube was associated with a significantly increased dose to the HRCTV D90, and no significant change in the D2cc to the rectum.However, for some patients the use of a rectal tube may worsen dosimetric parameters if the rectum is pushed anteriorly towards the target volume by the relatively stiff rectal tube.Further work is required in identifying patients who may not benefit from use of a rectal tube.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.002 | 0.006 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.010 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".