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Record W2514758198

Facial effects of the Warner protocol for children with Down syndrome

2002· article· en· W2514758198 on OpenAlexvenueno aff
Robert J. van Thiel

Bibliographic record

VenueJournal of orthomolecular medicine · 2002
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicConnective tissue disorders research
Canadian institutionsnot available
Fundersnot available
KeywordsPercentileMedicinePsychological interventionDown syndromePhysical therapyIntervention (counseling)PediatricsProtocol (science)Prospective cohort studyDemographySurgeryAlternative medicineMathematicsStatisticsNursing
DOInot available

Abstract

fetched live from OpenAlex

Children with Down syndrome tend to be short. There is no known effective medical intervention to address height for these children. Since 1986, Dr. F. Jack Warner has specialized in seeing people with Down syndrome. Warner uses an unconventional protocol which includes interventions such as nutrition (HAP Caps, flaxseed oil, N, N-dimethylglycine), physical therapy, ophthalmology, and conventional medicine. Warner claims his interventions can help make children with Down syndrome more like non-Down's children. The purpose of this investigation was to determine if the Warner protocol could improve growth for children with Down syndrome. Method: This investigation used a pretest-posttest, natural control group design. An independent investigation of a random sample of Warner's records was performed. Height and weight data, based on age, were compared against growth grids for Down's children for two visits to the Warner House: the initial measurement and the final measurement. Results: An analysis of the sample suggests that the combined interventions appear to significantly improve height (p <.001) for children with Down syndrome. The average (mean) height percentile grew from 63.4 to 76.0 (gender was not a significant factor). Although weight percentile went from 52.2 to 56.2 (p=.209), there was a significant difference in gender with the male percentile increasing from 45.2 to 53.7 (P=.035), while female percentile decreased from 60.9 to 59.3 (p=.755). Conclusion: Nutrition is the most likely intervention to be credited for improving height. A prospective study to test this position should be performed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.327
Threshold uncertainty score0.292

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.292
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2002
Admission routes1
Has abstractyes

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