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PP.34.05

2015· article· ja· W2518092381 on OpenAlexaboutno aff
M. Vorobyeva, Alexandra Doronina, S. V. Villevalde, Zhanna Kobalava

Bibliographic record

VenueJournal of Hypertension · 2015
Typearticle
Languageja
FieldMedicine
TopicGDF15 and Related Biomarkers
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineMontreal Cognitive AssessmentDyslipidemiaInternal medicineAtrial fibrillationStroke (engine)Diabetes mellitusPopulationRenal functionCardiologyLipid profileCholesterolDementiaObesityDiseaseEndocrinology

Abstract

fetched live from OpenAlex

Objective: Stroke is a common long-term condition with an increasing incidence as the population ages. Stroke symptoms often include cognitive impairment. Dyslipidemia is a well-known risk factor for stroke. The aim of the study was to investigate the cognitive impairment, lipid profile characteristics and patterns of statin therapy in patients with non-hemorrhagic stroke. Design and method: In 100 patients with acute ischemic stroke (42% male, 69.2 ± 8.9 (M ± SD) years, current smoking 30%, abdominal obesity 74%, arterial hypertension 97%, myocardial infarction 14%, previous non-hemorrhagic stroke 35%, diabetes mellitus 19%, brachiocephalic atherosclerosis 78%, atrial fibrillation 23%, chronic heart failure NYHA II/III 32/4%, chronic kidney disease 12%, estimated glomerular filtration rate 67.1 ± 17.1 ml/min/1.73 m2, alcohol abuse 12%, anemia 13%, previous statin therapy 9% the cognitive impairment, lipid profile characteristics and frequency of statin therapy were assessed. Cognitive functions were evaluated by using the Montreal Cognitive Assessment (MoCA) scale. Results: 96 (96%) patients had cognitive disfunction: 20.1 ± 4.3 scores by MoCA scale. 86 (86%) patients had dyslipidemia. The mean levels of lipids were 5.5 ± 1.3 mmol/l for total cholesterol (TC), 1.1 ± 0.3 mmol/l for HDL-C, 3.6 ± 0.9 mmol/l for LDL-C and 2.1 ± 0.6 mmol/l for triglycerides (TG). 17 (17%) patients were treated by statins during hospitalization. All of them took a low-dose statin. Conclusions: 96% of patients with non-hemorrhagic stroke have cognitive impairment according to MoCA scale, 86% of patients have dyslipidemia, only 9% and 17% of patients receive low-dose statin therapy ambulatory and at hospital respectively. There is a substantial gap between the guidelines and real practice of statin therapy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.050
Threshold uncertainty score0.000

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0040.003
Open science0.0020.003
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.9500.962

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.262
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2015
Admission routes1
Has abstractyes

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