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PP.34.05

2015· article· ja· W2518092381 on OpenAlexaboutno aff
M. Vorobyeva, Alexandra Doronina, S. V. Villevalde, Zhanna Kobalava

Bibliographic record

VenueJournal of Hypertension · 2015
Typearticle
Languageja
FieldMedicine
TopicGDF15 and Related Biomarkers
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineMontreal Cognitive AssessmentDyslipidemiaInternal medicineAtrial fibrillationStroke (engine)Diabetes mellitusPopulationRenal functionCardiologyLipid profileCholesterolDementiaObesityDiseaseEndocrinology

Abstract

fetched live from OpenAlex

Objective: Stroke is a common long-term condition with an increasing incidence as the population ages. Stroke symptoms often include cognitive impairment. Dyslipidemia is a well-known risk factor for stroke. The aim of the study was to investigate the cognitive impairment, lipid profile characteristics and patterns of statin therapy in patients with non-hemorrhagic stroke. Design and method: In 100 patients with acute ischemic stroke (42% male, 69.2 ± 8.9 (M ± SD) years, current smoking 30%, abdominal obesity 74%, arterial hypertension 97%, myocardial infarction 14%, previous non-hemorrhagic stroke 35%, diabetes mellitus 19%, brachiocephalic atherosclerosis 78%, atrial fibrillation 23%, chronic heart failure NYHA II/III 32/4%, chronic kidney disease 12%, estimated glomerular filtration rate 67.1 ± 17.1 ml/min/1.73 m2, alcohol abuse 12%, anemia 13%, previous statin therapy 9% the cognitive impairment, lipid profile characteristics and frequency of statin therapy were assessed. Cognitive functions were evaluated by using the Montreal Cognitive Assessment (MoCA) scale. Results: 96 (96%) patients had cognitive disfunction: 20.1 ± 4.3 scores by MoCA scale. 86 (86%) patients had dyslipidemia. The mean levels of lipids were 5.5 ± 1.3 mmol/l for total cholesterol (TC), 1.1 ± 0.3 mmol/l for HDL-C, 3.6 ± 0.9 mmol/l for LDL-C and 2.1 ± 0.6 mmol/l for triglycerides (TG). 17 (17%) patients were treated by statins during hospitalization. All of them took a low-dose statin. Conclusions: 96% of patients with non-hemorrhagic stroke have cognitive impairment according to MoCA scale, 86% of patients have dyslipidemia, only 9% and 17% of patients receive low-dose statin therapy ambulatory and at hospital respectively. There is a substantial gap between the guidelines and real practice of statin therapy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.099
Threshold uncertainty score0.591

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.262
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2015
Admission routes1
Has abstractyes

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