Prospects of enhancing dietary zinc bioavailability with food-derived zinc-chelating peptides
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Zinc is an essential micronutrient that strongly influences human health and nutrition through its involvement in several biological processes. Zinc functions as structural and functional component of many transcription factors and enzymes that regulate cell growth, gene expression, and immune response, and its deficiency can lead to retarded growth and impaired immune functions. The physiological functions of zinc are dependent on its bioavailability in tissues, which in turn depends on intestinal absorption of dietary zinc. The presence of dietary fibre and phytates impedes intestinal zinc absorption, as they can form insoluble complexes with zinc, decreasing its bioavailability. Peptides derived from food proteins can enhance zinc absorption and bioavailability. Peptides that contain amino acid residues such as cysteine, histidine, serine, aspartate and glutamate can chelate divalent metals, including zinc, forming soluble metal coordinate complexes. The structure-function relationship of zinc-chelating peptides and the stability of the peptide-metal complexes to gastrointestinal digestion are critical to their relevance in human nutrition and health promotion.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it