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Acute Responses Of A 90 K Cycle To Substrate Utilization, Muscle Deoxygenation, GET, And Performance

2016· article· en· W2520646946 on OpenAlexaff
Michael Bitel, Mikaela Barnes, Mike McCrudden, Glen R. Belfry

Bibliographic record

VenueMedicine & Science in Sports & Exercise · 2016
Typearticle
Languageen
FieldMedicine
TopicSports Performance and Training
Canadian institutionsWestern University
Fundersnot available
KeywordsDeoxygenationCycle ergometerOxidative phosphorylationChemistryAnimal scienceGlycolysisBlood lactateSubstrate (aquarium)Respiratory exchange ratioInternal medicineEndocrinologyHeart rateBiochemistryMetabolismMedicineBiologyCatalysis

Abstract

fetched live from OpenAlex

PURPOSE: To observe the acute responses of a 90 k cycle on VO2max, gas exchange threshold (GET), critical power (CP), substrate use, blood lactate, and muscle deoxygenation during ramp (RAMP) and CP testing. METHODS: 12 male cyclists (28±6y; VO2max 4.2±0.5 L/min) performed RAMP and CP tests on a cycle ergometer, pre and post 90 k moderate intensity cycle on the open road. The RAMP test (30 W/min) was used to determine VO2max and GET whereas the CP test demonstrated peak power and CP. Breath-by-breath pulmonary VO2 and muscle deoxygenation (HHb) was measured during both RAMP and CP tests. Blood lactate concentration was collected pre and post, both tests. RESULTS: RAMP: Decreased VCO2/VO2 (RER) and carbohydrate oxidation at CP (pre 1.08 ± 0.08, post 1.03 ± 0.06; pre 5.8 g/min, post 5.07 g/min; P<0.05; P<0.05) demonstrating increased activation of glycolytic oxidative phosphorylation and reduced substrate glycolytic phosphorylation was observed. VO2 at GET was unchanged, whereas work rate decreased (pre 2.5 ± 0.43 L/min, post 2.38 ± 0.4 L/min; pre 209 ± 33 W, post 188±29 W; P>0.05; P<0.05) implicating increased oxidative phosphorylation from fat. Post ride, post RAMP test blood lactate, peak work rate and VO2max were lower (pre 12.08 ± 2.28 mmol/L, post 9.16 ± 3.3 mmol/L; pre 392 ± 29 W, post 361 ± 28 W; pre 4.2 ± 0.46 L/min, post 3.85 ± 0.45 L/min; P<0.05). Increased HHb from 175-310 s post cycle, with no change in VO2 suggests reduced blood flow distribution (BFD) (P<0.05; P>0.05). CP: CP and associated VO2 were similar pre to post-ride (pre 300 ± 35 W, post 306 ± 39 W; pre 3.92 ± 0.32 L/min, post 3.76 ± 0.43 L/min; P>0.05). Whereas RER decreased pre- to post-ride at CP (pre 1.15 ± 0.07, post 1.08 ± 0.07; P<0.05) suggesting lower substrate glycolytic phosphorylation. Reduced HHb from 10-75 s post cycle, with no change in VO2 suggests improved BFD (P<0.05; P>0.05). Decreased power output from 10-95 s (P<0.05) post ride, coupled with the lower blood lactate (pre 15.38 ± 2.75 mmol/L, post 10.62 ± 2.18 mmol/L; P<0.05) suggests lower anaerobic glycolytic phosphorylation. CONCLUSION: The acute response to a long duration cycle enables cyclists to perform at CP and GET with lower glycogen utilization due to up regulation of glycolytic oxidative phosphorylation. Chronic long duration training sessions (90 k) may increase aerobic power from carbohydrates.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.306
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2016
Admission routes1
Has abstractyes

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