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Record W2524582348 · doi:10.1136/bmj.i5085

Transcatheter or surgical aortic valve replacement for patients with severe, symptomatic, aortic stenosis at low to intermediate surgical risk: a clinical practice guideline

2016· article· en· W2524582348 on OpenAlexaff
Per Olav Vandvik, Catherine M Otto, Reed Siemieniuk, Rodrigo Bagur, Gordon Guyatt, Lyubov Lytvyn, Richard Whitlock, Trond Vartdal, David Brieger, Bert Aertgeerts, Susanna Price, Farid Foroutan, Michael Shapiro, Ray Mertz, Frederick A. Spencer

Bibliographic record

VenueBMJ · 2016
Typearticle
Languageen
FieldMedicine
TopicCardiac Valve Diseases and Treatments
Canadian institutionsPopulation Health Research InstituteInstitute for Clinical Evaluative SciencesHospital for Sick ChildrenWestern UniversityLondon Health Sciences CentreMcMaster UniversityToronto General HospitalUniversity Health NetworkSickKids FoundationUniversity of Toronto
Fundersnot available
KeywordsMedicineStenosisGuidelinePerioperativeAortic valve replacementAortic valve stenosisClinical PracticeSurgeryCardiology

Abstract

In patients with symptomatic severe aortic stenosis but at lower risk of perioperative death, how do minimally invasive techniques compare with open surgery? Prompted by a recent trial, an expert panel produced these recommendations based on three linked rapid systematic reviews

Stored with the screening record, where it is evidence for the labels above.

How this classification was reachedexpand

The three-model screen

all 5,600 screened works →

All three models called this out of scope.

stratum: aff_core · design weight: 5595.24 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: policy
about Canada: no
confidence: high

Clinical practice guideline on aortic valve replacement; recommendations answering a clinical question.

GPT-5.6 (high)OUT
genre: policy
about Canada: no
confidence: high

This clinical practice guideline answers a treatment question using systematic reviews rather than studying synthesis methodology.

Grok 4.5OUT
genre: policy
about Canada: no
confidence: high

Clinical practice guideline on aortic valve replacement drawing on systematic reviews to answer a care question.

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.013
metaresearch head score (Gemma)0.044
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.013
Threshold uncertainty score0.000

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0130.044
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0050.006
Bibliometrics0.0030.002
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0040.001
Research integrity0.0070.007
Insufficient payload (model declined to judge)0.0020.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.386
Teacher spread0.365 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations93
Published2016
Admission routes1
Has abstractyes

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Same venueBMJSame topicCardiac Valve Diseases and TreatmentsFrench-language works237,207