Prevalence of Hemoglobinopathies and Thalassemia Carriers in Women of Reproductive Age Group Especially the Prospective Mothers: A Single Center Study at West Bengal
Bibliographic record
Abstract
Background: Hemoglobinopathies are group of diseases characterized by abnormalities both quantitative and qualitative in the production of hemoglobin. In India, major concerned hemoglobinopathic disorders are sickle cell anemia and beta-thalassemia. The aim of the study was to prevent the birth of first thalassemic child by screening pregnant women before 17 weeks of gestation and offering prenatal diagnosis if needed and to increase the awareness among general population about prevention of birth of genetically abnormal child. Methods: Blood samples were tested for complete blood count and hemoglobin electrophoresis. Results: During the study period, a total of 1,083 women were screened; among them 50 women who carried abnormal pattern (beta-thalassemia) were detected. The prevalence of carriers was 4.61%. Apart from I²-thalassemia and hemoglobin E carrier (1.10%), two additional variants were encountered. Conclusion: The data regarding prevalence and distribution can be useful in prevention and management of various hemoglobinopathies. J Hematol. 2016;5(3):99-102 doi: http://dx.doi.org/10.14740/jh297w Â
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".