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Record W2560212153 · doi:10.2967/jnmt.125.270161

2024 Update of the North American Consensus Guidelines for Pediatric Administered Radiopharmaceutical Activities

2025· article· en· W2560212153 on OpenAlex
S. Ted Treves, Frederic H. Fahey, Valentina Ferrer Valencia, Nanci A. Burchell, Christiane Sarah Burton, Michael Czachowski, Frederick D. Grant, Hollie Lai, Ruth Lim, Helen Nadel, Miguel Hernandez Pampaloni, Neeta Pandit‐Taskar, Marguerite T. Parisi, Victor J. Seghers, Summit Shah, Barry L. Shulkin, Lisa J. States, Reza Vali, Don C. Yoo, Katherine Zukotynski

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Nuclear Medicine Technology · 2025
Typearticle
Languageen
FieldMedicine
TopicChildhood Cancer Survivors' Quality of Life
Canadian institutionsMcMaster UniversityHospital for Sick Children
Fundersnot available
KeywordsMedicineConsensus conferenceNuclear medicineMedical physicsInternal medicine

Abstract

fetched live from OpenAlex

The 2024 update of the North American consensus guidelines for pediatric administered radiopharmaceutical activities (NAGL) is presented. Under the auspices of the Image Gently Alliance, a working group of 19 pediatric nuclear medicine experts, including clinicians, technologists, and physicists, worked for 2 y to update the 2016 NAGL, its most recent version. Building on previous success, the current recommendations regarding pediatric diagnostic nuclear medicine were reviewed systematically regarding their continued pertinence, the need for modification, and whether any recent protocols should be added. The working group reviewed and approved the 2024 update of the NAGL, and the update was subsequently approved by the Image Gently Alliance in the spring of 2024. None of the 23 protocols listed in the 2016 NAGL were removed; however, 9 were modified, and 6 new protocols (<sup>13</sup>N-NH<sub>3</sub> and <sup>83</sup>Rb for cardiac imaging; <sup>18</sup>F-DOPA, <sup>68</sup>Ga-DOTATATE, <sup>68</sup>Ga-DOTATOC, and Na<sup>123</sup>I for thyroid cancer imaging) were added. Five of 6 new protocols involve PET imaging, reflecting an increase in the routine use of PET in children in the past decade. This 2024 update addresses the impact of advances in imaging equipment, reconstruction, image processing, and clinical practice and the introduction of new radiopharmaceutical agents into the practice of pediatric nuclear medicine.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.329
Threshold uncertainty score0.490

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.408
Teacher spread0.345 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it