106 Salvage of Post-Prostatectomy Injection Therapy (With and Without Venoseal for Cvod) Treatment Failures by Injection Therapy Coupled With Novel Silicone Loop Occlusion Device
Bibliographic record
Abstract
Men with refractory erectile dysfunction (ED) post radical prostatectomy (RP) often demonstrate concurrent cavernous veno-occlusive disease (CVOD). Failing injection therapy or injection therapy (ICI) coupled with a Venoseal (VS) or similar device most often limits pt treatment options to surgery (penile prosthesis - PP). Given limited options for refractory ED/CVOD in this group, we sought to determine whether a novel soft silicone loop occlusive device (SSLO) satisfying FDA and Health Canada standards could salvage ICI-VS failures. Eleven men at least 18 months post-RP, having failed ICI and ICI-VS for satisfactory sexual function but attaining EHS scores of 1 or 2, comprised the study group. Prior to study, in-office testing and then teaching of ICI at 1 cc DS trimix (mean no. of visits 4), follow-up (FU) at 4 weeks at which point the VS was added to ICI with repeat in-office testing/teaching with 1 cc DS trimix, and FU at 8 weeks of use was performed. No patients attained an EHS 3 or better in office or at home. Options for treatment were reviewed, including surgery, VED, or an in-office test with ICI 1 cc DS trimix and the SSLO March 5 2016. The 11 patients choosing to trial ICI-SSLO at home underwent review May 14 and June 4 2016.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.003 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".