Cigarette Smoking as a Relative Risk Factor for Metabolic Syndrome
Bibliographic record
Abstract
Background: Metabolic syndrome (MS) is a clustering of risk factors, such as central obesity, insulin resistance, diabetes, hypertension and atherosclerosis. Cigarette smoking is a strong risk factor for cardiovascular diseases; therefore, smoking may be considered as an important risk factor for MS. Smokers are at greater risk than non-smokers to become insulin-resistant and develop cardiovascular diseases. This study aimed to explore the association of cigarette smoking with MS and its components among Iraqi adults who were already smokers for more than 10 years. Methods: This clinical study was conducted on 80 adult Iraqi subjects, aged 50 - 70 years. Subjects were divided into two groups according to their smoking status. Standard questionnaire was completed regarding smoking habits, medications, past medical history and physical activity. Blood pressure measurements and biochemical analysis involving fasting serum glucose and serum lipid profile (total cholesterol, high-density lipoprotein (HDL)-cholesterol and triglycerides (TG)) were done. The diagnosis of MS was based on the American Heart Association (AHA) and the National Heart, Lung, and Blood Institute (NHLBI) criteria. Results: According to the AHA definition, this study showed that MS was higher in smokers than in non-smokers with the relative risk for MS. Furthermore, obesity and dyslipidemia were found to be in 65.6% and 80% of both study groups, respectively. Systolic (P = 0.026) and diastolic blood pressures (P = 0.03) were significantly higher in smokers compared with non-smokers. The present study clearly showed that total serum cholesterol, HDL-cholesterol and low-density lipoprotein (LDL)-cholesterol serum levels were higher in the smoker group; however, a statistical significance was not obtained. Serum TG level was significantly higher (P = 0.025) in smokers than in non-smokers. The remarkable increase in the prevalence of MS among the smokers and non-smokers was correlated with the involvement of more than one component of MS according to the AHA and NHLBI criteria. Conclusions: The present study showed that tobacco smoke exposure increases the incidence of or worsens MS. Obesity and overweight give a comparable risk to smoking in adult subjects. Reducing the rate of cigarette smoking provides a beneficial effect on cardiovascular risk factors of this syndrome, such as body weight, blood pressure, blood cholesterol, and serum glucose. J Endocrinol Metab. 2016;6(6):178-182 doi: https://doi.org/10.14740/jem390e
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".