Calciphylaxis of the breast with associated diffuse dermal angiomatosis
Bibliographic record
Abstract
In 2013, approximately 660,000 Americans had end stage renal disease (ESRD), requiring either dialysis or transplantation. Up to 5% of dialysis dependent patients may develop calcific uremic arteriolopathy or calciphylaxis (CPX) with vascular medial calcification of arterioles and subcutaneous capillaries with superimposed thrombotic occlusion. Risk factors other than chronic kidney disease include: female gender, diabetes mellitus, liver disease, warfarin, obesity, and hypercoagulability. CPX usually affects adipose rich areas on the trunk and proximal extremities, however an increasing number of reports document breast involvement. We report a case of unilateral breast CPX with a protracted clinical course and superimposed diffuse dermal angiomatosis (DDA). These two unusual cutaneous vaso-occlusive conditions have rarely been reported simultaneously. We review the literature and discuss the relationship and predisposing factors between these two conditions. We believe our case suggests that DDA could be precipitated by CPX secondary to calcific vaso-occlusion.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".