SP537BRAIN MAGNETIC RESONANCE AND COGNITIVE FUNCTION CHANGES IN MAINTAINED HEMODIALYSIS PATIENTS
Bibliographic record
Abstract
Introduction and Aims: In this study, we want to investigate cerebrovascular lesions in our maintained hemodialysis (MHD) patients , by their brain magnetic resonance images and cognitive function changes. Methods: This is a cross-sectional study at our hemodialysis center. We totally screened 270 MHD patients, and we recruited 117 of them. Demographic informations were collected. Clinical features, laboratory data, and MR images were assessed. Cognitive function was evaluated with C-MMSE (Chinese Mini Mental Test Examination) and C-MoCA (Chinese Montreal Cognitive Assessment). Results were analyzed with SPSS. Results: (1) Average age was 56.0±12.5 yrs, average hemodialysis voltage was 73.5±60.8 months. Only 5.1% patients had clinical history of cerebral infarction or hemorrhage. (2) Average hemodialysis time was 11.3±2.0hr. Pre-hemodialysis blood pressure was 142.7/80.3 ±18.2/12.9mmHg, post-hemodialysis blood pressure was 130.2/79.1 ± 23.4/14.9 mmHg, inter-hemodialysis blood pressure was 135.5/79.0±20.3/11.3mmHg. 16.2% patients had intra-hemodialysis hypotension. spKT/V was 1.45±0.25,Hgb was 111.3±12.5. (3) MRI results: 12% patients had cerebral artery stenosis, 5.1% patients had cortical infarcts,39.3% patients had lacunar infarcts, 47% patients had microbleeds, 7.7% patients had chronic hematoma. 52.1% patients had abnormal brain whiter matter lesions (WMLs)–whiter matter hyperintensity. (4) In cognitive function evaluation, 20.9% patients had abnormal MMSE scores, but 65.2% patients had abnormal MoCA results. (5) WMLs had relation to dialysis voltage. The patients with cortical infarcts were on higher pre-hemodialysis systolic blood pressure. The patients with chronic hematoma were with longer dialysis voltage, lower post-hemodialysis blood pressure. Brain artery stenosises were associated with lower pre-dialysis blood pressure. The number of lacunar infarcts was associated with pre-dialysis serum creatinine, but negatively correlated with post-hemodialysis blood pressure. The patients with history of intra-hemodialysis hypotension had more lacunar infarcts, microbleed lesions and more serious brain artery stenosises.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".