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Record W2566665215 · doi:10.1093/ajcp/138.suppl2.51

Synovial Fluids: Crystals and Culture: A One-Year Retrospective

2012· article· en· W2566665215 on OpenAlexaff
John Penman, Gordon Hoag

Bibliographic record

VenueAmerican Journal of Clinical Pathology · 2012
Typearticle
Languageen
FieldMaterials Science
TopicMetal Alloys Wear and Properties
Canadian institutionsIsland Health
Fundersnot available
KeywordsSynovial fluidMedicinePathology

Abstract

fetched live from OpenAlex

The objective was to document the number, type, stability, and laboratory findings of synovial fluids submitted to our hospital laboratories in a 12-month period (April 1, 2011–March 31, 2012). Our laboratories serve 1,000 hospital beds and 400,000 outpatients. All microscopy was performed by ourselves, and patient records were reviewed to determine the joint and crystals and bacterial culture results. Microscopy was repeated on 114 negative samples at 8 hours and about 50 positive samples up to 24 hours later. Of 255 orders, 70% were from knee; 10% from hips; 5% each from shoulders, elbows, and ankles; and 2% from wrists. Crystals were identified in 40%: 48% urate and 48% pyrophosphate; less than 1% both; 4% other crystal types (mostly unidentified and thought to be due to medications). The ratio of urate/pyprophosphate crystals was equal in knees; about 2:1 in elbows, ankles, and wrists; and 0:1 in hips or shoulders. None of 114 initially crystal-negative samples were positive on reexamination after 8 hours. No positive cases became negative. Only hip, knee, shoulder, and elbow fluids yielded positive bacterial cultures, 20% of which also contained pyrophosphate crystals. Organisms isolated were MRSA (19/31) Staphylococcus warneri (3), various streptococci (5), and miscellaneous (4). Knee fluids comprised the vast majority of fluids submitted with hips a distant second; 40% of knees yielded crystals; more from ankles and shoulders and least from elbows and hips. Urate and pyrophosphate crystals occurred equally in knees, but urate crystals were not found in hips or shoulders, and less than 1% of fluids contained both urate and pyrophosphate crystals. Of the fluids, 12% had positive cultures; 20% also contained crystals; all pyrophosphate. The majority of positive cultures were due to gram-positive cocci, mainly Staphylococcus aureus. Crystal findings appear to be very stable for 8 hours or more after sampling.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.564
Threshold uncertainty score0.414

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.353
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2012
Admission routes1
Has abstractyes

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