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Record W2567732588 · doi:10.1016/j.jsxm.2016.08.016

Standards for Clinical Trials in Male and Female Sexual Dysfunction: III. Unique Aspects of Clinical Trials in Male Sexual Dysfunction

2017· article· en· W2567732588 on OpenAlexaff
William A. Fisher, Ilan Gruenwald, Emmanuele A. Jannini, Ahinoam Lev‐Sagie, Lior Löwenstein, Robert E. Pyke, Yacov Reisman, Dennis A. Revicki, Eusebio Rubio‐Aurioles

Bibliographic record

VenueThe Journal of Sexual Medicine · 2017
Typearticle
Languageen
FieldMedicine
TopicHormonal and reproductive studies
Canadian institutionsWestern University
Fundersnot available
KeywordsClinical trialSexual dysfunctionFemale sexual dysfunctionPopulationPsychologyClinical psychologyMedicinePsychiatryInternal medicine

Abstract

fetched live from OpenAlex

This series of articles, Standards for Clinical Trials in Male and Female Sexual Dysfunction, began with the discussion of a common expected standard for clinical trial design in male and female sexual dysfunction, a common rationale for the design of phase I to IV clinical trials, and common considerations for the selection of study population and study duration in male and female sexual dysfunction. The second article in this series discussed fundamental principles in development, validation, and selection of patient- (and partner-) reported outcome assessment. The third and present article in this series discusses selected aspects of sexual dysfunction that are that are unique to male sexual dysfunctions and relevant to the conduct of clinical trials of candidate treatments for men.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.578
metaresearch head score (Gemma)0.664
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: Methods
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.422
Threshold uncertainty score0.521

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.5780.664
Meta-epidemiology (narrow)0.0020.003
Meta-epidemiology (broad)0.0070.006
Bibliometrics0.0080.006
Science and technology studies0.0060.021
Scholarly communication0.0200.009
Open science0.0080.009
Research integrity0.0220.029
Insufficient payload (model declined to judge)0.0020.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.379
GPT teacher head0.534
Teacher spread0.155 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations19
Published2017
Admission routes1
Has abstractyes

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