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Record W2567958807 · doi:10.1177/153567600200700303

Risk Assessment for Enteric Pathogens in the Biosafety Level 2 Laboratory

2002· article· en· W2567958807 on OpenAlex
Betty Kupskay

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueApplied Biosafety · 2002
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBacillus and Francisella bacterial research
Canadian institutionsCanadian Science Centre for Human and Animal Health
Fundersnot available
KeywordsBiosafetySalmonellaBiological safetyAerosolizationMicrobiologyMedicineBiologyBiotechnologyInhalationBacteria

Abstract

fetched live from OpenAlex

There is some general confusion regarding when to use a biological safety cabinet (BSC) to minimize risk from aerosol formation in Biosafety Level 2 (BSL'2) laboratories that handle enteric pathogens. A risk assessment was conducted to determine the risk involved in performing some standard microbiological manipulations. Although enteric organisms are not known to be infectious via inhalation, it was felt ingestion of droplets deposited around the work area may cause laboratory-acquired infection. Manipulations of Salmonella spp., Shigella spp., Escherichia coli 0157, and other E. coli have resulted in laboratory-acquired infection due to improper laboratory technique. Routine procedures, for example opening screw-capped bottles and wet petri dish covers, improper use of needle and septum, streaking plates, pipetting, slide agglutination, and microscopic preparations, were found to have potential to cause aerosol formation. Proper microbiological technique in combination with primary containment devices (e.g., biological safety cabinets) has been found to reduce the risk of laboratory-acquired infections when working with enteric pathogens. Laboratory workers must ensure that they use any means available to minimize these risks.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.903
Threshold uncertainty score0.569

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.271
Teacher spread0.246 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it